Wu Su, PhD, Principle Investigator

Director of Center for Innovative Drug Development

Director of Guangzhou Key Laboratory of Intelligent Drug Conjugates

EDUCATION

2005-2007 Ph.D in Organic Chemistry, Eberhard Karls Universität Tübingen, Germany

1997-2000 M.S. in Biochemistry, Lanzhou University, China

1986-1990 B.S. in Plant physiology, Peking University, China

RESEARCH EXPERIENCE

2024-Nov.        Principal Investigator&Director

                         Center for Innovative Drug Development, Greater Bay Area Institute of Precision Medicine (Guangzhou)

2018-2023        Director of Medicinal Chemistry

                         AstraZeneca (Sweden)

2017-2018        Director

                          Zhuhai Institute of Advanced Technology

2012-2018        Principal Investigator&Assistant Director

                         Institute of Biomedicine and Biotechnology, SIAT-CAS

2008-2012        EPSRC Postdoctoral Fellow

                          University of Leicester

SELECTED PUBLICATIONS

1. Li M, Lu D, Cheng Y, Wu C, Zhang J, Shi W, Ding Z, Li Y, Cheng B, Lin X, Shao X, Li H, Fang L, Liu K, Su W. A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo. Biochem Biophys Res Commun. 2021 Sep 24;571:167-173.

2. Ao L, Wu C, Liu K, Wang W, Fang L, Huang L, Su W. Polydopamine-Derivated Hierarchical Nanoplatforms for Efficient Dual-Modal Imaging-Guided Combination in Vivo Cancer Therapy. ACS Appl Mater Interfaces. 2018 Apr 18;10(15):12544-12552.  

3. Pan Z, Wu C, Wang W, Cheng Z, Yao G, Liu K, Li H, Fang L, Su W. Total Synthesis and Stereochemical Assignment of Gymnopeptides A and B. Org Lett. 2017 Sep 1;19(17):4420-4423.  

4. Tan Y, Wang W, Wu C, Pan Z, Yao G, Fang L, Su W. Myristic acid-modified thymopentin for enhanced plasma stability and immune-modulating activity. Int Immunopharmacol. 2017 Jun; 47:88-94.

5. Liu X, Wang Y, Yang D, Zhang J, Liu D, Su W. Catalytic Asymmetric Inverse-Electron-Demand 1,3-Dipolar Cycloaddition of C,N-Cyclic Azomethine Imines with Azlactones: Access to Chiral Tricyclic Tetrahydroisoquinolines. Angew Chem Int Ed Engl. 2016, 4;55(28):8100-3.  

6. Yao G, Pan Z, Wu C, Wang W, Fang L, Su W. Efficient Synthesis and Stereochemical Revision of Coibamide A. J Am Chem Soc. 2015 Oct 28;137(42):13488-91.  

7. Huang L, Ao L, Wang W, Hu D, Sheng Z, Su W. Multifunctional magnetic silica nanotubes for MR imaging and targeted drug delivery. Chem Commun (Camb). 2015 Mar 4;51(18):3923-6.

8. Fang L, Yao G, Pan Z, Wu C, Wang HS, Burley GA, Su W. Fully automated synthesis of DNA-binding Py-Im polyamides using a triphosgene coupling strategy. Org Lett. 2015 Jan 2;17(1):158-61.  

Email： suwu@ipm-gba.org.cn