Guiyang Yao, PhD, co-PI

EDUCATION

2013-2016 Ph.D in Chemical Engineering and Technology, Southeast University, China

(2014-2016 Intern ( Ph.D student) of SIAT-Chinese Academy of Sciences)

2010-2013 M.S. in Organic Chemistry, Guangxi Normal University, China

2006-2010 B.S. in Applied Chemistry, Jiangsu Normal University, China

RESEARCH EXPERIENCE

2022-Present.   Principal Investigator

                         Center for Innovative Drug Development, Greater Bay Area Institute of Precision Medicine (Guangzhou)

2019-2022       Postdoctoral

                         Host:  Professor Peter Hildebrandt

                         Technical University of Berlin, Germany

2017-2018       Postdoctoral Fellow of Alexander von Humboldt Foundation

                          Host:  Professor Roderich D. Süssmuth

                         Technical University of Berlin, Germany

SELECTED PUBLICATIONS

1. G. Yao, S. Kosol, M. T. Wenz, E. Irran, B.G. Keller, O. Trapp, R. D. Süssmuth*,The occurrence of ansamers in the synthesis of cyclic peptides, Nature Communications, 2022, 13, 6488. (highlighted by editor)

2. G. Yao, C. H. Knittel, S. Kosol, M. T. Wenz, B. G. Keller, H. Gruß, A. C. Braun, C. Lutz, T. Hechler, A. Pahl, R. D. Sussmuth*, Iodine-Mediated Tryptathionine Formation Facilitates the Synthesis of Amanitins, J. Am. Chem. Soc., 2021, 143, 14322-14331. (highlighted by Faculty 1000)

3. G. Yao, J. Joswig, B. G. Keller, R. D. Süßmuth*. Total Synthesis of the Death Cap Toxin Phalloidin: Atropoisomer Selectivity Explained by Molecular-Dynamics Simulations. Chem.-Eur. J. 2019, 25, 8030– 8034. 

4. G. Yao, W. Wang, L. Ao, Z. Cheng, C. Wu, Z. Pan, J.i Liu, K. Liu, H. Li, W. Su*, L. Fang*. Improved total synthesis and biological evaluation of coibamide A analogues. J. Med. Chem. 2018, 61, 8908-8916.

5. G. Yao, Z. Pan, C. Wu, W. Wang, L. Fang*, W. Su*. Efficient Synthesis and Stereochemical Revision of Coibamide A. J. Am. Chem. Soc. 2015, 137, 13488–13491.  (highlighted by 有机化学)

PATENT

Hendrik Gruß, Christian Lutz, Roderich Süßmuth, Guiyang Yao, Caroline Knittel, Simone Kosol, Andi Mainz, Method for synthesis of thioether-containing peptides 2020. WO2021/250059A1

Email： yaoguiyang@ipm-gba.org.cn